HƯỚNG NGHIÊN CỨU
KẾT QUẢ NGHIÊN CỨU
Các công bố quốc tế trong 5 năm gần nhất:
Nguyen Thi Minh Thuan, Tran Huu Truong. Validation of a simple HPLC method to quantify mycophenolic acid concentrations in human plasma. MedPharmRes 2021; 5(2):1-6.
Nguyen Thi Minh Thuan, Le Thi Thao Nguyen. Inhibitory effect of medicinal plants on in vitro human peripheral blood mononuclear cell proliferation, interleukin-2 secretion and antioxidant activity. MedPharmRes 2021; 5(1):23-29.
Nguyen Thi Minh Thuan, Nguyen Thi Khanh Linh. Simultaneous determination of salbutamol and clenbuterol in human plasma using liquid chromatography coupled to tandem mass spectrometry. Pharmaceutical Sciences Asia 2019;46(2):120-128.
Nguyen Thi Bao Anh, Nguyen Thi Minh Thuan. Evaluation of clenbuterol-induced changes in blood biochemical parameters in white mice. Pharmaceutical Sciences Asia 2018;45(1):45-53.
M. Laura Mascotti, Hemant Kumar, Quoc-Thai Nguyen, Maximiliano Juri Ayub, Marco W. Fraaije. Reconstructing the evolutionary history of F420-dependent dehydrogenases. Scientific Reports 2018;8:17571.
Quoc-Thai Nguyen, Elvira Romero, Willem P. Dijkman, Suzan Pantaroto de Vasconcellos, Claudia Binda, Andrea Mattevi and Marco W. Fraaije. Structure-based engineering of Phanerochaete Chrysosporium alcohol oxidase for enhanced oxidative power toward glycerol. Biochemistry 2018;57(43):6209-6218.
Sam Mathew, Milos Trajkovic, Hemant Kumar, Quoc-Thai Nguyen, Marco W. Fraaije. Enantio- and regioselective ene reductions using F420H2-dependent enzymes. Chemical Communications 2018;54(79):11208-11211.
Nguyen, L. V., Nguyen, K. D. A., Ma, C.-T., Nguyen, Q.-T., Nguyen, H. T. H., Yang, D.-J., … Doan, K. V. (2021). p-Coumaric acid enhances hypothalamic leptin signaling and glucose homeostasis in mice via differential effects on AMPK activation. International Journal of Molecular Sciences, 22(3), 1431.
Le, M.-T., Mai, T. T., Huynh, P. N. H., Tran, T.-D., Thai, K.-M., & Nguyen, Q.-T. (2020). Structure-based discovery of interleukin-33 inhibitors: a pharmacophore modelling, molecular docking, and molecular dynamics simulation approach. SAR and QSAR in Environmental Research, 31(12), 883–904.
Vo, C.-V. T., Luu, N. V. H., Nguyen, T. T. H., Nguyen, T. T., Ho, B. Q., Nguyen, T. H., … Nguyen, Q.-T. (2022). Screening for pancreatic lipase inhibitors: evaluating assay conditions using p-nitrophenyl palmitate as substrate. All Life, 15(1), 13–22.
Mai, T. T., Nguyen, P. G., Le, M.-T., Tran, T.-D., Huynh, P. N. H., Trinh, D.-T. T., … Thai, K.-M. (2022). Discovery of small molecular inhibitors for interleukin-33/ST2 protein--protein interaction: A virtual screening, molecular dynamics simulations and binding free energy calculations. Molecular Diversity, 1–20.
Tran, T.-T.-N., Tran, Q.-H., Nguyen, Q.-T., Le, M.-T., Trinh, D.-T. T., & Thai, K.-M. (2022). Identification of potential interleukin-8 inhibitors acting on the interactive site between chemokine and CXCR2 receptor: A computational approach. Plos One, 17(2), e0264385.
Tran, Q.-H., Nguyen, Q.-T., Vo, N.-Q.-H., Mai, T. T., Tran, T.-T.-N., Tran, T.-D., … Thai, K.-M. (2022). Structure-based 3D-Pharmacophore modeling to discover novel interleukin 6 inhibitors: An in silico screening, molecular dynamics simulations and binding free energy calculations. Plos One, 17(4), e0266632.
Nguyen, L. C., Le, T. T. A., Dang, T. N., Dao, M. Q., Nguyen, T. H., Vo, M. H., … Others. (2022). Natural mimetic 4-benzyloxychalcones as potent pancreatic lipase inhibitors: Virtual screening, synthesis and biological evaluation. Phytochemistry Letters, 51, 28–33.
Fraaije, M. W., Guzman, E. R., Mattevi, A., & Nguyen, Q.-T. (2019) Mutant alcohol oxidases and use thereof in the conversion of diols and polyols. WO Patent 2019.212.351
Tran, T. T. N., Tran, Q. H., Nguyen, Q. T., Le, M. T., Trinh, D. T. T., Tran, V. H., & Thai, K. M. (2022). LY3041658/interleukin-8 complex structure as targets for IL-8 small molecule inhibitors discovery using a combination of in silico methods. SAR and QSAR in Environmental Research, 33(10), 753–778.
Tran, Q.-H., Cao, H.-N., Nguyen, D.-N., Tran, T.-T.-N., Le, M.-T., Nguyen, Q.-T., … Thai, K.-M. (2023). Targeting Olokizumab-Interleukin 6 interaction interface to discover novel IL-6 inhibitors. Journal of Biomolecular Structure and Dynamics, 1–13.
Tran, T.-T.-N., Tran, Q.-H., Duong, C. Q., Nguyen, Q.-T., Tran, V.-T., Le, M.-T., … Thai, K.-M. (2023). In silico approach to identify novel allosteric intracellular antagonist for blocking the interleukin-8/CXCR2 receptor signaling pathway. Journal of Biomolecular Structure and Dynamics, 1–14.
Rotilio, L., Boverio, A., Nguyen, Q.-T., Mannucci, B., Fraaije, M., & Mattevi, A. (2023). A biosynthetic aspartate N-hydroxylase performs successive oxidations by holding intermediates at a site away from the catalytic center. Journal of Biological Chemistry, 104904.
Nguyen Thi Minh Thuan*, Nguyen Thi Khanh Linh. Simultaneous determination of salbutamol and clenbuterol in human plasma using liquid chromatography coupled to tandem mass spectrometry. Pharmaceutical Sciences Asia (E-ISSN 2586-8470), 2019: 46(2), 120-128 (Scopus Q4)
Nguyen Thi Minh Thuan*, Le Tran Bao Uyen, Le Duy Hoang Chuong, Tran Ton. External quality assessment for dual detection of HBsAg and anti-HCV in serum. Pharmaceutical Sciences Asia (E-ISSN 2586-8470), 2022: 49(2), 69-76 (Scopus Q3)
Nguyen Thi Minh Thuan*, Tran Duy Khoa, Chau Van Tuan. Prescription of antipsychotics and prevalence of metabolic syndrome in Vietnamese inpatients with schizophrenia. Pharmaceutical Sciences Asia (E-ISSN 2586-8470), 2022: 49(4), 364-371 (Scopus Q3)
Nguyen Thi Minh Thuan*, Le Thi Thao Nguyen. Inhibitory effect of medicinal plants on in vitro human peripheral blood mononuclear cell proliferation, interleukin-2 secretion and antioxidant activity. Medpharmres (ISSN print 1859- 1779; ISSN online 2615-9139), 2021: 5(1), 23-29 (ACI)
Nguyen Thi Minh Thuan*, Tran Huu Truong. Validation of a simple HPLC method to quantify mycophenolic acid concentrations in human plasma. Medpharmres (ISSN print 1859-1779; ISSN online 2615-9139), 2021: 5(2), 1-6
Nguyen Thi Minh Thuan*, Nguyen Hue Minh. Validation of a simple HPLC method to quantify methotrexate concentrations in human plasma. Medpharmres (ISSN print 1859-1779; ISSN online 2615-9139), 2022: 6(1), 27-32
Thuan Thi Minh Nguyen and Dung Thi Van Nguyen. Assessment of stability of HbA1c levels in human whole blood samples using immunoassays. Medpharmres (ISSN print 1859-1779; ISSN online 2615-9139), 2023: 7(3), 83-89